BIOL 4640 / 8646 · 3 credits · Donald Rowen, PhD · ALLWINE 305 · Mon/Wed/Fri 11 to 11:50 AM

Molecular Microbiology, Fall 2026

Diversity in structures, genetics, metabolism and regulation observed in bacteria, compared to other microorganisms. Five units, four unit exams, and an optional comprehensive final that can replace one of the first three exams.

Quick start

Predicted schedule of topics & exam dates

Chapter numbers below are Slonczewski, Foster & Zinser 6e, exactly as listed in the syllabus. Rowen labels this schedule "predicted": dates can shift. Every section opens in the Textbook reader.

UnitTopicChapter(s)Assessment / notes
1Methods for studying microorganismsNotes
1Methods for culturing and counting microbial cells4.3 to 4.4
1Methods for observing microbial cells2.1 to 2.6
2Features of microbial genomes and chromosomes7.1 to 7.6, 6.3
2Genomic sequencing and annotationA3.6, 9.5
2Genome evolution9
2Microbial phylogeny and taxonomy17.3, 17.5, 18.1Exam 1: Oct 5 (done)
3Bacterial external structures3.6
3Bacterial envelope and cell wall3.3
3Cell membrane and transport3.2
3Bacterial internal structuresnone listed
3Bacterial cell division3.4 to 3.5
3Viruses6No lecture Oct 26 · Exam 2: Oct 28 (done)
4Energetics and catabolism13Lectures 23 to 24 so far (Oct 21, 23)
4Aerobic/anaerobic respiration, lithotrophy and phototrophy14
4Biosynthesis and CO₂ fixation15.1 to 15.2Exam 3: Nov 23
5Transcription and translation8.1 to 8.5
5Molecular regulation10, 12.1
5Biofilms and cell differentiation4.5, 12.2
5Adaptations to environmental influences4.6, 5.1 to 5.6Exam 4: Dec 16, 10 to 11:59 AM · optional Final Dec 16 to 18

What the exam pattern means for you

  • Exam 1 (Oct 5) covers Units 1 + 2: methods, genomes, phylogeny. It is the only exam that carries two units, so it is the longest stretch of material.
  • Exams 2, 3, 4 cover Units 3, 4, 5 respectively.
  • Exam 4 and the optional final both fall in finals week: Exam 4 on Dec 16 morning, the comprehensive final somewhere in Dec 16 to 18. If you are happy with your first three scores you can skip the final entirely.

Grading

AssessmentPointsShare
Best four of five exams (4 × 100 pts): four unit exams plus the optional comprehensive final400 pts~73%
Homework assignments, including the Microbe Presentation~150 pts~27%
Total~550 pts100%

Grading scale. A+ 96 to 100 A 92 to 95.9 A− 89 to 91.9 B+ 86 to 88.9 B 82 to 85.9 B− 79 to 81.9 C+ 76 to 78.9 C 69 to 75.9 D 60 to 68.9

The syllabus scale lists no C− and no F band; C spans a wide 69 to 75.9%, and anything below 60% is by implication failing.

Policies worth memorizing

  • Homework is due 11:59 PM on the posted date. Late work loses 3% per day, capped at 50% off, so a late assignment is always worth turning in.
  • Missed exam: if the reason is valid (Rowen's judgment) and you notify him in advance or shortly after, you may make it up.
  • The optional final replaces one of exams 1 to 3, not exam 4.
  • Academic dishonesty: zero on the first offense, failing grade in the course on the second.

Instructor & logistics

InstructorDonald Rowen, PhD
LecturesMon / Wed / Fri, 11:00 to 11:50 AM · Allwine 305
OfficeAllwine Hall 114J
Office hoursTuesday & Wednesday 10 to 11 AM, or by appointment · Zoom available
Emaildrowen@nebraska.edu, his stated best contact method
Phone402-554-2143 (voicemail)
Cross-listedBIOL 4640 / 8646, graduate section runs alongside
Syllabus4640-Syllabus-Fa2026_v4.pdf, hosted here; also on Canvas as .docx and .pdf

Accessibility. Accommodations are provided for students registered with the Accessibility Services Center who request them sufficiently in advance: 104 H&K · 402.554.2872 · unoaccessibility@unomaha.edu.

Course objectives

By the end of the course Rowen expects you to be able to:

  1. Describe the function and importance of structures found in bacterial cells.
  2. Predict the properties of a bacterium from an analysis of its genome.
  3. Describe some of the diversity in energy-generating metabolic pathways found in bacteria.
  4. Describe ways that bacteria regulate their processes and adapt to their environment.

Objective 2 is the one that shapes the exams most: Unit 2 is genome-first, and "here is a genome annotation, what can this organism do?" is the natural question format.